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668 result(s)
Development - Molecular Biology
CCDC28A deficiency causes head-tail coupling defects and immotility in murine spermatozoa
Nena Stojanovic, Rosario Ortiz Hernández, Nayeli Torres Ramírez, Olga Margarita Echeverría Martínez, Abrahan Hernández Hernández & Hiroki Shibuya
(2024) Nature, Scientific Reports volume 14, Article number: 26808 https://doi.org/10.1038/s41598-024-78453-9
Metabolism - Molecular Biology
GCKIII Kinases Control Hepatocellular Lipid Homeostasis via Shared Mode of Action
Emmelie Cansby, Mara Caputo, Emma Andersson, Rasool Saghaleyni, Marcus Henricsson, Ying Xia, Bernice Asiedu, Matthias Blüher, L. Thomas Svensson, Andrew J. Hoy, Margit Mahlapuu
(2024) Journal of Lipid Research, doi: https://doi.org/10.1016/ j.jlr.2024.100669.
Molecular Biology - Metabolism
HNF1β bookmarking involves Topoisomerase 1 activation and DNA topology relaxation in mitotic chromatin
Alessia Bagattin, Salvina Laura Tammaccaro, Magali Chiral, Munevver Parla Makinistoglu ∙ Nicolas Zimmermann ∙ Jonathan Lerner, Serge Garbay ∙ Nicolas Kuperwasser, Marco Pontoglio
(2024) Cell Reports, Volume 43, Issue 10114805October 22, doi.org/10.1016/j.celrep.2024.114805
Molecular Biology - Cell Biology
SLC26A4-AP-2 mu2 interaction regulates SLC26A4 plasma membrane abundance in the endolymphatic sac
Hyun Jae Lee, Cristina Fenollar-Ferrer, Kevin Isgrig, Ya-Xian Wang, Kerstin Valente, Juleh Eide, Keiji Honda, Wade W. Chien, Ronald S. Petralia, Lijin Dong, Thomas B. Friedman, Juan S. Bonifacino , Andrew J. Griffith, and Isabelle Roux
(2024) Science Advances 9 Oct 2024 Vol 10, Issue 41 DOI: 10.1126/sciadv.adm8663
Nanobodies
NEAT1 modulates the TIRR/53BP1 complex to maintain genome integrity
Susan Kilgas, Aleem Syed, Patrick Toolan-Kerr, Michelle L. Swift, Shrabasti Roychoudhury, Aniruddha Sarkar, Sarah Wilkins, Mikayla Quigley, Anna R. Poetsch, Maria Victoria Botuyan, Gaofeng Cui, Georges Mer, Jernej Ule, Pascal Drané & Dipanjan Chowdhury
(2024) Nature Communications volume 15, Article number: 8438, DOI: 10.1038/s41467-024-52862-w
Microbiology - Molecular Biology
Anaplasma phagocytophilum invasin AipA interacts with CD13 to elicit Src kinase signaling that promotes infection
Mary Clark H. Lind, Waheeda A. Naimi, Travis J. Chiarelli, Tavis Sparrer, Mallika Ghosh, Linda Shapiro, Jason A. Carlyon
(2024) Host-Microbial Interactions Research Article 26 September, DOI: https://doi.org/10.1128/mbio.01561-24
Microbiology - Molecular Biology
Orientia tsutsugamushi Ank5 promotes NLRC5 cytoplasmic retention and degradation to inhibit MHC class I expression
Haley E. Adcox, Jason R. Hunt, Paige E. Allen, Thomas E. Siff, Kyle G. Rodino, Andrew K. Ottens & Jason A. Carlyon
(2024) Nature Communications volume 15, Article number: 8069
Molecular Biology - Cell Biology
Interaction between the TBC1D24 TLDc domain and the KIBRA C2 domain is disrupted by two epilepsy-associated TBC1D24 missense variants
Risa Tona, Sayaka Inagaki, Yasuko Ishibashi, Rabia Faridi, Rizwan Yousaf1 ∙ Isabelle Roux, Elizabeth Wilson, Cristina Fenollar-Ferrer, Wade W. Chien, Inna A. Belyantseva,Thomas B. Friedman
(2024) JBC 107725 August DOI: 10.1016/j.jbc.2024.107725
Nanobodies
SHANK3 depletion leads to ERK signalling overdose and cell death in KRAS-mutant cancers
Johanna Lilja, Jasmin Kaivola, James R. W. Conway, Joni Vuorio, Hanna Parkkola, Pekka Roivas, Michal Dibus, Megan R. Chastney, Taru Varila, Guillaume Jacquemet, Emilia Peuhu, EmilyWang, Ulla Pentikäinen, Itziar Martinez D. Posada, HellyehHamidi, Arafath K. Najumudeen , Owen J. Sansom, Igor L. Barsukov, Daniel Abankwa, Ilpo Vattulainen, Marko Salmi & Johanna Ivaska
(2024) Nature Communications volume 15, Article number: 8002
Metabolism - Molecular Biology - Cell Biology
The E3 ubiquitin-protein ligase Nedd4-2 regulates the sodium chloride cotransporter NCC but is not required for a potassium-induced reduction of NCC expression
Rosenbaek LL, Petrillo F, van Bemmelen MX, Staub O, Murali SK, Fenton RA.
(2022) . Front Physiol. ; 13:971251. doi: 10.3389/fphys.2022.971251. PMID: 36160843; PMCID: PMC9490057.
Molecular Biology - Cell Biology
A non‐canonical scaffold‐type E3 ligase complex mediates protein UFMylation
Peter JJ, Magnussen HM, DaRosa PA, Millrine D, Matthews SP, Lamoliatte F, Sundaramoorthy R, Kopito RR, Kulathu Y.
(2022) . EMBO J. Nov 2;41(21):e111015. doi: 10.15252/embj.2022111015. PMID: 36121123; PMCID: PMC9627666.
Plant Biology - Molecular Biology
Medicago truncatula SOBIR1 controls pathogen immunity and specificity in the Rhizobium‐legume symbiosis
Baptiste Sarrette, Thi-Bich Luu, Alexander Johansson, Judith Fliegmann, Cécile Pouzet, Carole Pichereaux, Céline Remblière, Laurent Sauviac, Noémie Carles, Emilie Amblard, Valentin Guyot, Maxime Bonhomme, Julie Cullimore, Clare Gough, Christophe Jacquet, Nicolas Pauly
(2024) Plant, Cell and Environment, 03 September https://doi.org/10.1111/pce.15071